Life expectancy for people with HIV has increased by an average of 13 years since the late 1990s thanks to better HIV treatment, a study says.
Researchers said it meant HIV was now effectively a chronic condition like diabetes, rather than a fatal disease, the Lancet reported.
The team, involving Bristol University staff, looked at over 43,000 patients.
The study found a person now diagnosed at 20 years old could expect to live for another 49 years.
But the Antiretroviral Therapy Cohort Collaboration, which includes scientists from across Europe and Northern America, warned this was still short of the life expectancy for the wider population which stands at about 80.
Antiretroviral treatment for HIV consists of drugs which work against the infection itself by slowing down the replication of the virus in the body.
This method of therapy was introduced in the 1990s, but has since become more effective and better tolerated.
The researchers looked at life expectancy during three time periods after the introduction of the drugs - 1996-9, 2000-2 and 2003-5 - in high income countries.
Just over 2,000 patients died during the study periods.
They found that while patients aged 20 diagnosed in the 1990s could expect to live another 36 years, that had increased by 13 years by 2003-5.
During the middle time period, life expectancy stood at an extra 41 years.
Success
Researcher Professor Jonathan Sterne said: "These advances have transformed HIV from being a fatal disease, which was the reality for patients before the advent of combination treatment, into a long-term chronic condition."
He added the development was a "testament" to the success of the anti-HIV drugs.
But the researchers warned those diagnosed later in the course of the infection had a much shorter life expectancy.
Marc Thompson, deputy head of health promotion at the Terrence Higgins Trust, said: "HIV medication has become much more effective since the early days.
"There has been great progress, but research needs to continue, especially for those who have developed resistance to some drugs and are running out of options."
But he added the study also highlighted the need for early diagnosis, pointing out an estimated a third of people with HIV do not know they have it.
Deborah Jack, of the National Aids Trust, said: "Hopefully, this study will encourage more people to come forward for testing but we need to better educate doctors about the signs and symptoms to look for.
"Society also needs to catch-up with the fact that HIV is a long-term condition that thousands of people in the UK are living with everyday.
1990s thanks to better HIV treatment, a study says
WASHINGTON - Tractor-trailer and bus drivers in the United States have suffered seizures, heart attacks or unconscious spells behind the wheel that led to deadly crashes on highways. Hundreds of thousands of drivers carry commercial licenses even though they also qualify for full federal disability payments, according to a new U.S. safety study obtained by The Associated Press.
The problems threatening highway travelers persist despite years of government warnings and hundreds of deaths and injuries blamed on commercial truck and bus drivers who blacked out, collapsed or suffered major health problems behind the wheels of vehicles that can weigh 40 tons or more.
The U.S. agency responsible for cracking down on unfit truckers, the Federal Motor Carrier Safety Administration, acknowledges it hasn't completed any of eight recommendations that U.S. safety regulators have proposed since 2001. One would set minimum standards for officials who determine whether truckers are medically safe to drive. Another would prevent truckers from "doctor shopping" to find a physician who might overlook a risky health condition. It's unclear whether any of the eight recommendations will be done before President Bush leaves office.
"We have a major public safety problem, and we haven't corrected it," said Gerald Donaldson, senior research director at the Washington-based Advocates for Highway and Auto Safety, whose members include consumer, health and safety groups and insurance companies. "You have an agency that is favorably disposed to maintaining the integrity of the industry's economic situation."
Truckers violating federal medical rules have been caught in every state, according to a review by the AP of 7.3 million commercial driver violations compiled by the Transportation Department in 2006, the latest data available. Texas, Maryland, Georgia, Florida, Indiana, Pennsylvania, Illinois, Michigan, Alabama, New Jersey, Minnesota and Ohio were states where drivers were sanctioned most frequently for breaking medical rules, such as failing to carry a valid medical certificate. Those 12 states accounted for half of all such violations in the United States.
Consider these cases:
_A Florida bus driver who suffers from lung disease and uses three daily inhalers to control breathing told congressional investigators that he "occasionally blacks out and forgets things." He works as a substitute driver despite not having a medical certificate, and his commercial license expires in 2010. The driver, who was not identified but will figure prominently in a congressional hearing this week, has collected Social Security benefits since 1994. He confided to investigators that he "gets winded" walking to his mailbox but has no problem driving a passenger bus.
_A Virginia trucker with a prosthetic leg from a farm accident more than 10 years ago is permitted to drive tanker trucks until at least 2012, even though he doesn't have the proper federal paperwork required for amputees. Virginia revoked the medical license for the official who approved him to drive over charges the official was caught illegally distributing controlled substances.
_George Albright Jr., 61, smashed his 70,000-pound tractor-trailer into congested traffic on Interstate 70 in June 2006, killing four women in a Ford sedan about 30 miles east of Columbia, Mo. Albright's employer agreed earlier this year to pay $18 million in a settlement. A Missouri jury acquitted Albright this month on four counts of second-degree involuntary manslaughter, after his lawyers argued in court that a diabetic episode "put him in an altered state of consciousness." Albright wasn't injured.
_A gasoline tanker plunged from an overpass and exploded in flames on Interstate 95 near Baltimore in January 2004, killing four people. Witnesses reported the driver slumped over the wheel. Maryland investigators concluded the driver, Jackie M. Frost, had suffered a heart attack or other medical emergency, but his family disputed that.
_The driver of a 15-passenger "Tippy Toes" day-care bus traveling 63 mph on Interstate 240 in Memphis, Tenn., in April 2002 crashed into a bridge, killing the driver and four of the six children aboard. The National Transportation Safety Board said the driver, Wesley B. Hudson, 27, fell asleep, "quite likely due to an undiagnosed sleep disorder." Investigators said children sometimes had to wake up Hudson, whom the NTSB described as obese and a marijuana user.
_A 55-passenger bus rolled off Interstate 610 in New Orleans in May 1999, killing 22 passengers. The NTSB said the bus driver, Frank Bedell, 46, suffered life-threatening kidney and heart conditions but held a valid license and medical certificate. Moments before the crash, a passenger recounted seeing the driver slumped in his seat. Bedell died three months later of an apparent heart-related illness. Investigators said he was treated at least 20 times in the 21 months before the accident for various ailments.
Some truckers said the government should enforce existing rules, not make new ones.
"Do you enjoy your clothing and house? Without the truck driver you would have none of it," said Gary Hull, 52, a trucker for a Louisiana company, as he drove from Edinburg, Texas, to Mansfield, La. "Our economy is based on the truck. People don't understand the ramifications of making it more restrictive for truck drivers to drive."
Hull said most drivers are hard workers who earn a modest salary and cope with rising diesel prices. New regulations could add to costs and force truckers to evade the rules, he said.
"There are enough government regulations as it is," agreed Ken Cornell, interviewed at a truck stop. "The medical profession should be able to take care of it. If they have a condition where they shouldn't be driving, they should be able to catch them."
The Transportation Department said 5,300 people died in crashes involving large commercial trucks or buses in 2006, the latest year for which figures are available, and about 126,000 more were injured. A federal safety study last summer found that cases where drivers fell asleep, suffered heart attacks or seizures or otherwise were physically impaired were a leading cause of serious crashes involving large trucks. But those cases included healthy drivers who fell asleep.
"The problem is major," said Dr. Kurt Hegmann, chairman of the federal motor carrier administration's medical oversight board, which is urging more doctor visits in many cases for truckers with serious medical conditions. "It's one of the biggest causes of occupational death in the United States today."
Congress may take action soon. The House Transportation and Infrastructure Committee, led by Rep. James Oberstar, D-Minn., will conduct oversight hearings Thursday. One proposal would create a clearinghouse for drug test results for commercial truck drivers to make it easier for employers to conduct checks. Oberstar's committee asked the Government Accountability Office to investigate unfit truck drivers.
The 30-page GAO study, obtained by the AP in advance of its release later this week, said 563,000 commercial drivers were determined by the Veterans Affairs Department, Labor Department or Social Security Administration to also be eligible for full disability benefits over health issues. It said disability doesn't necessarily mean a driver is unfit to operate a commercial vehicle, but its investigators found alarming examples that raised doubts about the safety of the nation's highways. They identified more than 1,000 drivers with vision, hearing or seizure disorders, which generally would prohibit a trucker from obtaining a valid commercial license.
The chief safety officer for the Federal Motor Carrier Safety Administration, Rose McMurray, acknowledged problems that could lead to unfit truck drivers on the roads. She blamed delays in reforms on a lack of federal money and difficulty coordinating with 50 states. McMurray said changes to strengthen the medical oversight program may not be done for months or even years.
"We have done a lot to recognize the deficiencies in our medical oversight program, and the building blocks we're establishing are very smart and very strong," McMurray said.
Families of crash victims said stronger safety rules can't happen soon enough.
William Hieronymus II of Salina, Kan., said he remembers eating cereal each morning with his 10-month-old son. His son William and wife, Amanda, died in May 2005 when a truck crossed a median and struck their SUV.
The driver, Scott A. Wegrzyn, pleaded guilty to two counts of vehicular homicide. Prosecutors said Wegrzyn knew he suffered from sleep apnea and went to a second doctor without disclosing the condition to obtain the medical certification he needed to drive.
"I try to go through a day without crying," Hieronymus said during Wegrzyn's trial. "I wonder every day what (Will) would have grown up to be, what he would have stood for."
Article from:
http://news.yahoo.com/s/ap/20080721/ap_on_go_ot/unfit_drivers
There is a huge variation in cancer survival rates across the world, a global study shows.
The US, Australia, Canada, France and Japan had the highest five-year survival rates, while Algeria had the worst, Lancet Oncology reported.
The UK fared pretty poorly, trailing most of its western European neighbours - although the data is from the 1990s since when survival rates have risen.
Spending on health care was a major factor, the study of 31 countries said.
Researchers said higher spending often meant quicker access to tests and treatment.
The report is the first major study to compare cancer survival across five continents and has highlighted the stark differences in survival between poor and wealthy countries
Dr Lesley Walker, of Cancer Research UK
The research was carried out by more than 100 scientists across the world led by Professor Michel Coleman, of the London School of Hygiene and Tropical Medicine.
It involved analysing data on more than two million cancer patients who were diagnosed and treated during the 1990s.
The study showed the US had the highest five-year survival rates for breast cancer at 83.9% and prostate cancer at 91.9%.
Japan came out best for male colon and rectal cancers, at 63% and 58.2% respectively, while France fared best for women with those cancers at 60.1% and 63.9%.
The UK had 69.7% survival for breast cancer, just above 40% for colon and rectal cancer for both men and women and 51.1% for prostate cancer.
There were also large regional variations within the UK, which were linked to differences in access to care and ability of patients to navigate the local health services. Both are directly linked to deprivation.
A Department of Health spokesman said the report covered patients diagnosed between 1990 and 1994.
"Since that time, cancer survival rates in England have been steadily improving for but we accept that there is further work to do to reduce the gap between us and the rest of northern and western Europe and America."
Algeria, the only African country involved, came bottom in all types of cancer.
Survival
It meant an American man was four times more likely to survive prostate cancer than an Algerian, while a Japanese man was six times more likely to survive colon cancer.
Poland, Slovenia, Brazil and Estonia had survival rates half as good as the best performers.
The results closely mirrored the amount each country was spending on health during the period.
While the US led the way with more than 13% of gross domestic product spent on health, Canada, Australia and the best-performing European nations were all spending about 9% to 10%.
The UK was spending just over 7% but that figure has now been increased following record rises in the NHS budget to bring it much closer to the likes of France and Germany.
Algeria was spending around 4%.
The importance of money was further illustrated by an ethnic breakdown of outcomes in the US.
White Americans, who are on the whole wealthier and therefore more able to afford the insurance which underpins the US system, were up to 14% more likely than others to survive cancer.
Professor Coleman said some of the differences could be attributed to variations in "access to diagnostic and treatment services".
"This, of course, is associated with the amount of investment in technology such as CT scanners."
Dr Lesley Walker, Cancer Research UK's director of cancer information, added: "The report is the first major study to compare cancer survival across five continents and has highlighted the stark differences in survival between poor and wealthy countries."
Article From:
http://news.bbc.co.uk/2/hi/health/7510121.stm
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